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中国精品科技期刊2020
张昊彤,周雪巍,乔凯娜,等. 肽-钙螯合方式及吸收机制研究现状[J]. 食品工业科技,2024,45(19):383−391. doi: 10.13386/j.issn1002-0306.2023080325.
引用本文: 张昊彤,周雪巍,乔凯娜,等. 肽-钙螯合方式及吸收机制研究现状[J]. 食品工业科技,2024,45(19):383−391. doi: 10.13386/j.issn1002-0306.2023080325.
ZHANG Haotong, ZHOU Xuewei, QIAO Kaina, et al. Research Status of Peptide-Calcium Chelation and Absorption Mechanism[J]. Science and Technology of Food Industry, 2024, 45(19): 383−391. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023080325.
Citation: ZHANG Haotong, ZHOU Xuewei, QIAO Kaina, et al. Research Status of Peptide-Calcium Chelation and Absorption Mechanism[J]. Science and Technology of Food Industry, 2024, 45(19): 383−391. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023080325.

肽-钙螯合方式及吸收机制研究现状

Research Status of Peptide-Calcium Chelation and Absorption Mechanism

  • 摘要: 钙是人体必需的常量元素之一,科学补钙对维持生命健康具有重要意义,具有良好钙结合能力和高生物利用度的肽-钙螯合物也备受关注。本文综述了肽-钙螯合物中钙与肽的结合位点、结合模式、分子间作用力等内容。通过阐明游离钙和螯合钙的吸收途径,分析螯合钙易被肠道吸收的特点。肽-钙螯合物作为新型钙补充剂,来源丰富且生物利用度高,具有良好的经济开发价值和广阔的发展前景。在肽-钙螯合物的安全性、物理化学稳定性、消化稳定性以及螯合钙被肠道吸收后Ca2+的释放机制等方面的研究需要继续开展。本文旨在为新型钙补充剂的开发提供思路。

     

    Abstract: Calcium is one of the essential macro-elements in the human body. The scientific calcium supplementation is greatly significant to maintaining life and health. The peptide-calcium chelates with good calcium binding capacity and high bioavailability have attracted more attention. This work reviews the binding sites, binding modes, and intermolecular forces between calcium and peptides in peptide-calcium chelates. Compared with free calcium, chelated calcium is more easily absorbed in the intestine according to the summarization of the calcium absorption pathways. Peptide-calcium chelates, as a new generation of calcium supplements, have a rich source of raw materials, high bioavailability, good economic value, and broad development prospects. Further research is needed on the safety, physicochemical stability, digestive stability, and Ca2+ release mechanism of peptide-calcium chelates after intestinal absorption. This paper aims to provide new insight into the development of novel calcium supplements.

     

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