Abstract: To study microwave-assisted extraction for flavonoid of lavender produced in YiLi area. The single factor and orthogonal test was used to optimized process technology conditions of extracting flavonoids of lavender. The antioxidant activity of extracts was determined. The results showed that the microwave-assisted had good effect on extracting flavonoids of lavende. The optimum technological conditions:ethanol concentration 45%, ratio of material to liquid 1∶25, microwave power 500W, microwave time 25min. The extracting rate was 8.16%. Research results showed that the extracts of lavender had very strong scavenging ability on superoxide radical, DPPH free radicals and hydroxyl radicals. It had good inhibitory effect to linoleic acid oxidation reaction. Antioxidant activity increased with concentration enhanced.