Abstract: The garden stuff have polyphenol, various of organic acid, vitamin, and nutrients.All these made alcohol dehydrogenase and acetaldehyde dehydrogenase more active, and hasten the metabolism of alcohol.These also decomposed acetaldehyde which was produced by alcohol, and promoted it to translate into carbon dioxide and water that would be excreted from the body. Consequently it reduces or eliminates the injury caused by acetaldehyde, and relieved some untoward reaction such as dizziness, nausea, vomit and so on.With the study of the effect of drinking the mixed fruit juice including tomato pomelo and pear on sobering intoxicated person up, according to single factor experiment and orthogonal experiment that drinking mixed fruit juice ( 100mL) after drinking test alcohol ( 2mL /kg) half an hour later.It was found that the most effective combination was 25% tomato juice, 20% pomelo juice and 25% pear juice.