Abstract: Yam chips pretened by cassava chips is common and serious. In order to identify the yam chips and cassava chips in a more accurate way, multi- angle comprehensive identification techniques were established. In this study, multiple methods combined traditional methods and modern technologies to disprove were developed, including appearance identification, microscopic characteristics identification, hydrocyanic acid identification and allantoin identification.There was a big difference in terms of appearance, microscopic characteristics and physical and chemical indexes between yam chips and cassava chips, for example, negative yam chips and positive cassava chips were tested in hydrocyanic acid identification, while positive yam chips and negative cassava chips were tested in allantoin identification. Accurate conclusions can be drawn through the comprehensive judgment which overcomes the limitations of single detection means.This study provided a basis for regulatory controls and makes a great significance to ensure the safety and effectiveness of yam chips as both food and drug.