Abstract: In order to understand the nutritive value of Scatophagu sargus muscle,the nutritional composition and quality in muscle of ecological cultured S. sargus(2-age) in the winter were analyzed and evaluated by biochemical analysis methods. The results showed that the moisture,crude protein,crude fat,and crude ash contents of fresh muscles of S. sargus were 72.99%,18.63%,5.13%,and 1.29%,respectively. Glutamic acid,aspartic acid,lysine,and leucine were the highest contents in 18 kinds of found amino acids in muscles. Total amino acid(TAA),total essential amino acid(EAA),total half-essential amino acid(HEAA),and total delicious amino acid(DAA) contents of dry muscles were 68.99%,26.92%,6.13%,and 25.38%,respectively. The EAA/TAA,EAA/NEAA,and DAA/TAA were 39.01%,74.88%,and 36.80%,respectively. These met the Food and Agriculture Organization of the United Nations/Word Health Organization(FAO/ WHO) standards. According to nutrition evaluation in amino acids score(AAS) and chemical score(CS),the first limited amino acid was Val,the second limited amino acid was Ile,while according to nutrition evaluation in chemical score(CS),the first limited amino acid was Trp,the second limited amino acid was Val. The essential amino acid index(EAAI) and the ratio of branched chain amino acid to aromatic amino acid(F value) were 61.41 and 2.22,respectively. 7saturated fatty acids(SFA),6 mono-unsaturated fatty acids(MUFA),and 11 poly-unsaturated fatty acids(PUFA) were found in the dry muscle. The ∑SFA,∑MUFA, ∑ PUFA, ∑n3PUFA,EPA+DHA,and ∑ n6 PUFA were 38.27%,34.63%,27.09%,10.11%,7.30%,and 15.45%,respectively. The ∑SFA/∑UFA and ∑n3PUFA/∑n6PUFA were 0.62 and 0.65,respectively. Therefore,S. sargus was a kind of high nutritional value,delicious,and high quality fish,the muscle had certain health care function.