Abstract: Using the H₂O₂/Asc oxidation system to simulate the vitro oxidation, through the detection of physicochemical indexes, to study the effect of coregonus peled muscle'deteriorating through using different rinsing methods.The results showed that both 0.3% PG and 0.5% saline water can prevent oxidation of the protein, but PG was better than saline water, although the sodium ascorbate was used as antioxygen, it has effects of promote oxidation.Single factor experiment and response surface analysis were used to study the rinsing process.It shows when the concentration of 0.21% PG, rinse times for twice, rinse time for 6 min.Under the condition, the protein oxidation inhibited rate was 30.12%.The above conditions could effectively prevent protein oxidation caused coregonus peled muscle and increased the quality of coregonus peled.