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中国精品科技期刊2020
张棚,张海霞,田晓静,等. 乳铁蛋白生物活性及应用进展[J]. 食品工业科技,2021,42(13):404−411. doi: 10.13386/j.issn1002-0306.2020070367.
引用本文: 张棚,张海霞,田晓静,等. 乳铁蛋白生物活性及应用进展[J]. 食品工业科技,2021,42(13):404−411. doi: 10.13386/j.issn1002-0306.2020070367.
ZHANG Peng, ZHANG Haixia, TIAN Xiaojing, et al. Research Progress in Biological Activity and Application of Lactoferrin[J]. Science and Technology of Food Industry, 2021, 42(13): 404−411. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020070367.
Citation: ZHANG Peng, ZHANG Haixia, TIAN Xiaojing, et al. Research Progress in Biological Activity and Application of Lactoferrin[J]. Science and Technology of Food Industry, 2021, 42(13): 404−411. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020070367.

乳铁蛋白生物活性及应用进展

Research Progress in Biological Activity and Application of Lactoferrin

  • 摘要: 乳铁蛋白是一种铁结合型糖蛋白,由哺乳动物体内腺上皮细胞和中性粒细胞产生,为生物活性剂之一。它具有多种生物活性,包括抑菌、抗病毒、抗癌、抗炎、调节免疫和促骨生长等。它已经被用作一些口腔疾病的治疗、婴幼儿配方奶粉的营养强化剂、天然食品保鲜剂、天然化妆品,也可以作为许多棘手疾病辅助和预防治疗的合成原料或载体,被广泛应用在食品、医药、化妆品、畜牧养殖等领域,本文综述了乳铁蛋白的生物活性功能及其与微生物作用机制,并着重从以上五个领域介绍乳铁蛋白的开发与应用,旨在阐明乳铁蛋白的进一步应用前景。

     

    Abstract: Lactoferrin is an iron-binding glycoprotein produced by mammalian epithelial cells and neutrophils and is one of the bioactive agents. It has a variety of biological activities, including antibacterial, antiviral, anticancer, anti-inflammatory, immune regulation and bone growth.It has been used for some of the treatment of oral diseases, infant formula milk powder nutrition enhancer, natural food preservative, natural cosmetics, also can be used as the prevention and treatment of many difficult diseases auxiliary and synthetic raw material or carrier, is widely used in food, medicine, cosmetics, animal husbandry and aquaculture, and other fields. This paper summarizes the biological activities of lactoferrin function and microbial mechanism of action, and the development and application of lactoferrin are introduced emphatically from the above five areas, to clarify further application prospect of lactoferrin.

     

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