Abstract: Food-derived advanced glycation end products (AGEs) are irreversible covalent compounds formed by Maillard reactions of reducing sugars with proteins, nucleic acids and lipids under non-enzymatic conditions. It demonstrated that AGEs areclosely related to human health and involved in the occurrence and development of diabetes and its complications, Alzheimer's disease, intestinal diseases and other diseases. This paper briefly summarizes the harm of AGEs to human health in recent years, starting to foodborn AGEs, foucse on its hazards and prevention, in order to help in-depth research Ages. At the same time, ages inhibitors and blocks its functional channels and other means to prevent potential diseases are worthy of attention, may provide new directions for clinical treatment.