Abstract: This study aimed to clarify the maximum residue limit value of muskmelon, the additional types and their recommended values. Based on the quantitative analysis of 60 pesticide residues in 545 melon samples from 6 provinces in 2018 and 2019, the detected pesticide varieties were evaluated for chronic dietary intake risk (%ADI), acute dietary intake risk (%ARfD) and risk matrix. The quality and safety risks of pesticide residues in muskmelon were discussed, and the research and analysis on the relatively high risks of pesticide residues and the supplementary types and recommended values of maximum residue limits (MRLs) were carried out. The results showed that the acute and chronic dietary risks of residual pesticides were less than 100%, and the acute dietary risk of pendimethalin was relatively high, reaching 56.67%, among the residual pesticides, pyridaben, emamectin benzoate, and bifenthrin had relatively high risk. And 65.22% of residual pesticides had no MRLs, including 3 residual pesticides with relatively high risks. Based on the above analysis, pyridaben, emamectin benzoate, bifenthrin and pendimethalin had the characteristics of relatively high risk and no maximum residue limit. It was recommended to formulate corresponding limit values. The recommended values were as follows: 1, 0.05, 1, 3 mg·kg⁻¹.