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中国精品科技期刊2020
王艳辉,郑光耀,闫林林. 磁性分子印迹聚合物在天然活性物质分离纯化中的研究进展[J]. 食品工业科技,2023,44(11):442−450. doi: 10.13386/j.issn1002-0306.2022070368.
引用本文: 王艳辉,郑光耀,闫林林. 磁性分子印迹聚合物在天然活性物质分离纯化中的研究进展[J]. 食品工业科技,2023,44(11):442−450. doi: 10.13386/j.issn1002-0306.2022070368.
WANG Yanhui, ZHENG Guangyao, YAN Linlin. Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances[J]. Science and Technology of Food Industry, 2023, 44(11): 442−450. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022070368.
Citation: WANG Yanhui, ZHENG Guangyao, YAN Linlin. Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances[J]. Science and Technology of Food Industry, 2023, 44(11): 442−450. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022070368.

磁性分子印迹聚合物在天然活性物质分离纯化中的研究进展

Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances

  • 摘要: 磁性分子印迹聚合物是将磁性纳米粒子与分子印迹聚合物组装而成的一类新型分离材料,具有选择性高、易分离和易再生的特点,可被用于食品、药品检测前处理以及天然活性物质的分离纯化等领域。本文介绍了磁性分子印迹技术的制备原理和方法,重点综述了近5年(2017~2022)磁性分子印迹聚合物在多酚类、生物碱、有机酸、萜类以及生物大分子化合物等天然活性物质的分离纯化方面的研究进展,并针对当前分离纯化领域的研究难点进行了讨论,以期为高值化、低含量的天然活性成分的富集、纯化及其分析检测提供研究参考。

     

    Abstract: Magnetic molecularly imprinted polymers are novel separation materials assembled by magnetic nanoparticles and molecularly imprinted polymers, with specific selectivity, easy separation and regeneration, which can be used in the preliminary treatment of food and drugs, and the separation and purification of natural active substances. Herein, the preparation principle and method of magnetic molecular imprinting technology are elucidated, and the research progress (2017~2022) of magnetic molecular imprinting polymers in the separation and purification of natural active substances, such as polyphenols, alkaloids, organic acids, terpenoids, and macromolecules are reviewed. Meanwhile, the difficulties in the field of separation and purification are discussed. This review will provide reference for the enrichment, purification, analysis and detection of natural active substances.

     

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