Study on the stability of carboxymethylchitosan- coated proliposomes loaded coix seed oil

The storage stability and water rehydtrate stabilty of carboxymethylchitosan- coated proliposomes( CM-PL) containing coix seed oil was studied. On one hand,coix seed oil( CSO) leakage rate and malondialdehyde( MDA) production during CM- PL stored under different conditions( light,oxygen,temperature)was determined for storage stability evaluation.On the other hand,the leakage rate of CSO after CM- PL rehydrated in sodium chloride solution or glucose solution was also measured for rehydtrated stabilty evaluation. The results indicated that the stability of CM- PL could be affected by light,higher temperature and air contact,and the influence was in the order of temperature > air > light. Higher temperature resulted in larger CSO leakage,which accelerated lipid oxidation further.The non significant difference among light treated or air contact groups with their control samples maybe related to the carboxymethylchitosan layer,which could delay the light- oxidation and auto- oxidation to some extent.However,the protection was limited,and CM- PL should be stored under vacuum,avoid light and low temperature condition.As to the other aspect,CM- PL exhibited better tolerance on sodium chloride than glucose,with the leakage ratio of 14.3% and 21.1%,respectively after 14 days' storage.