Construction, Stability and in Vitro Digestive Properties of Quercetin Microcapsules

In this study, pectin was extracted from the residue of extracted jujube peel pigment to improve the stability and bioaccessibility of quercetin and increase the added value of jujube peel. Quercetin was then encapsulated using jujube peel pectin and cellulose nanocrystals as the wall material to construct a quercetin microcapsule system, and the preparation process was optimized through single-factor experiments and response surface tests. The microcapsules were characterized using environmental scanning electron microscopy (ESEM), Fourier transform infrared (FT-IR) spectroscopy, and thermogravimetric analysis (TGA), and their storage stability and in vitro simulated digestion properties were investigated. The results showed that the pectin extraction yield from the pigment residue was approximately 11-fold higher than that from the jujube peel, and the optimized quercetin microcapsule embedding rate was increased to 74.73%±2.45%, an improvement of over 15%. The ESEM revealed that the microcapsules were amorphous powders with wrinkled surfaces and visible dents. The particle size was 2.625±1.124 μm, with a PDI of 0.286±0.163, and their moisture content was 2.97%±0.40%. FT-IR spectroscopy and TGA confirmed the successful encapsulation of quercetin by the composite wall material. Quercetin retention in the microcapsules was spectroscopy 20% higher than that of free quercetin after 2 weeks of storage at 4 ℃ and 37 ℃, and the bio-accessibility of quercetin after encapsulation was 2.5-times that of free quercetin. Effective encapsulation and controlled release of quercetin with enhanced stability and improved bioaccessibility were achieved. This study provides a theoretical basis for the development of quercetin-related products and the comprehensive use of jujube peel, a byproduct of jujube processing.