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中国精品科技期刊2020
徐雪峰,代德财,闫浩,等. 槐糖脂对玉米醇溶蛋白-槲皮素纳米颗粒结构和性质的影响[J]. 食品工业科技,2024,45(17):1−8. doi: 10.13386/j.issn1002-0306.2023100157.
引用本文: 徐雪峰,代德财,闫浩,等. 槐糖脂对玉米醇溶蛋白-槲皮素纳米颗粒结构和性质的影响[J]. 食品工业科技,2024,45(17):1−8. doi: 10.13386/j.issn1002-0306.2023100157.
XU Xuefeng, DAI Decai, YAN Hao, et al. Effects of Sophorolipids on the Structure and Properties of Zein-Quercetin Nanoparticles[J]. Science and Technology of Food Industry, 2024, 45(17): 1−8. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023100157.
Citation: XU Xuefeng, DAI Decai, YAN Hao, et al. Effects of Sophorolipids on the Structure and Properties of Zein-Quercetin Nanoparticles[J]. Science and Technology of Food Industry, 2024, 45(17): 1−8. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023100157.

槐糖脂对玉米醇溶蛋白-槲皮素纳米颗粒结构和性质的影响

Effects of Sophorolipids on the Structure and Properties of Zein-Quercetin Nanoparticles

  • 摘要: 本研究制备了玉米醇溶蛋白-槲皮素纳米颗粒(Zein-Q),采用扫描电子显微镜、傅里叶红外光谱和荧光光谱等方法分析了槐糖脂(SL)对Zein-Q颗粒结构的影响,并研究了Zein-Q-SL复合纳米颗粒的抗氧化活性和抑菌性质。结果表明,Zein-Q纳米颗粒为平均粒径128 nm的球形结构,包封率和载药量分别为25.8%±1.28%和3.98%±0.24%,对DPPH·和ABTS+·的清除率为76.8%±0.9%和65.4%±1.2%。加入槐糖脂有助于形成分散性较好的纳米颗粒,且槐糖脂在氢键、静电作用力等作用下包覆于玉米醇溶蛋白-槲皮素纳米颗粒外层,形成粒径较大的球形结构,当Zein-Q:SL为3:4时,Zein-Q-SL复合纳米颗粒的包封率和载药量分别增加至73.6%±1.80%和7.98%±0.41%,对DPPH·和ABTS+·的清除率分别达到88.8%±1.0%和78.6%±1.5%。此外,复合纳米颗粒对大肠杆菌和金黄色葡萄球菌显示出较好的抑制活性。由此表明,生物表面活性剂槐糖脂有潜力作为提高玉米醇溶蛋白-槲皮素纳米颗粒结构稳定性和活性的修饰分子。

     

    Abstract: In this study, zein-quercetin (Zein-Q) nanoparticles were prepared and the effects of sophorolipids (SL) on the structure of Zein-Q nanoparticles were evaluated based on the combination of scanning electron microscopy, Fourier infrared spectroscopy and fluorescence spectroscopy. Their antioxidant and antibacterial properties were analyzed as well. The results showed that Zein-Q nanoparticles were spherical with an average particle size of 128 nm, the encapsulation efficiency and loading capacity were separately 25.8%±1.28% and 3.98%±0.24%, respectively, and its scavenging ability on DPPH· and ABTS+· were 76.8%±0.9% and 65.4%±1.2%. The addition of sophorolipids resulted in forming nanoparticles with good dispersion. The structural characteration results showed that sophorolipids were coated with the outer layer of zein-quercetin nanoparticles driven by the interaction of hydrogen bonding and electrostatic interaction, forming a spherical core-cell structure with a larger particle size. At Zein-Q:SL=3:4, the encapsulation efficiency and loading capacity of composite Zein-Q-SL nanoparticles were increased to 73.6%±1.80% and 7.98%±0.41%, respectively. The antioxidant activity of zein-quercetin nanoparticles was enhanced, which showed that the scavenging ability of composite Zein-Q-SL nanoparticles on DPPH· and ABTS+· reached 88.8%±1.0% and 78.6%±1.5%, respectively. In addition, the composite Zein-Q-SL nanoparticles showed a good inhibitory activity against Escherichia coli and Staphylococcus aureus. Thus, it can be concluded that biosurfactant sophorolipids have potential to be excellent modifier for enhancing the structural stability and activity of zein-quercetin nanoparticles.

     

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