Abstract: Blood oranges are characterized by the high concentration of anthocyanins, vitamin C, flavanones and hydroxycinnnamic acids.Furthermore, blood oranges possess bioactive functions with beneficial health effects, such as antioxidant capacity, inhibit tumorigenesis, lowering blood pressure, stimulating the immune system and reducing the occurrence of cardiovascular pathologies.Therefore, blood orange is a kind of fruit with higher nutritional value and commercial value.The progress of quantitative methods, isolation, purification and identification methods of the composition of blood orange were reviewed.The bioactive functions of blood oranges were also reviewed.The article provided a scientific basis for researching and developing the effective composition blood orange as effective ingredients, exploiting and utilizing blood orange resource for further.