Abstract: The tartary buckwheat red starter health wine was developed by using tartary buckwheat and glutinous rice as raw material, and sweet rice wine starter and yeast as saccharifying ferments.The optimum brewing scheme was determined as follows: 1∶1.5 the ratio of tartary buckwheat to glutinous rice, 0.6% sweet rice wine starter, 12%red starter, 1‰ yeast, 1 ∶1.5 the ratio of matetial to water, 28℃ fermentation temperature, 2 days saccharification time, and 6 days fermentation time. Ultimately the buckwheat red yeast health wine was tasty, and the alcohol content was 16.2%, pH was 4.32, total acid was 6.64 g /L, total sugar was 33.4g /L, amino nitrogen was 1.36 g /L, total amino acids was 2481.48 mg /mL, total flavonoids content was 928.18μg /mL, total polyphenol was 2243.01μg /mL.