Abstract: The anti-oxidation and anti-fatigue effects and their correlation of a peanut peptide beverage were investigated. A nutritionally balanced peanut peptide beverage was prepared using peanut peptide and other active substances as main active ingredients,an animal experiment consisting of three treatment groups and one control group was conducted to investigate anti-fatigue function and its effect on anti-oxidation indexes of the beverage. The results showed that compared with the control group,SOD contents of mice in the mediumand high-dose groups were significantly higher( p <0.05), MDA contents in the medium- and high-dose groups were significantly lower(p<0.05),the load swimming time and hepatic glycogen of all three treatment groups were significantly increased(p<0.05),while the whole blood lactic acid content and blood serum urea nitrogen significantly decreased(p<0.05). It could be concluded that the peanut peptide beverage had antifatigue function and anti-oxidation effect,and its anti-fatigue function was correlated to the SOD contents.