Abstract: This paper studied the in vivo antioxidation and immune modulation functions of anthocyanins from black rice.Saline solution was used as carriers,while vitamin C was used as positive control. Mice were fed with crude and pure anthocyanins at high,medium and low doses,respectively. After feeding for 30 days by mean of irrigation,the spleen and thymus indexes were detected,while T- AOC,SOD,GSH- Px,MDA and hydroxyl radical contents of serum,liver,heart and kidney were also determined.The results indicated that the anthocyanins could increase the spleen and thymus indexes,significantly increase the level of T- AOC,the activity of SOD and GSHPX,and reduce the contents of MDA and hydroxyl radical.Therefore,the anthocyanins have the functions of in vivo antioxidation and immune modulation.