Abstract: To study the antioxidant and antibacterial activity of different extracts from Sophora tonkinensis Gagnep.The chloroform,ethyl acetate,butanol and ethanol extracts were obtained by backflow-extraction. DPPH,ABTS,OH radical scavenging assays and reducing power assay were used to measure the antioxidant activity.And seven common test bacterias were employed to test the antibacterial activity in vitro. The result indicated that different extracts from Sophora tonkinensis Gagnep exhibited good antioxidant activity,especially for DPPH radical,which EC50<0.2mg/m L. The antibacterial experiments in vitro showed that the ethyl acetate extract had the obvious antibacterial effect on the Staphylococcus aureus and the minimum inhibitory concentration was0.313mg/m L.