Abstract: In order to improve the oxidation stability of soybean germ oil, this study used spray dying to prepare microcapsules.The aim of this study was to evaluate the influence of material ratio and process conditions on the microencapsulation of soybean germ oil by spray drying, and physicochemical properties, microscopic structure and oxidation stability were investigated at the same time.Particle size distribution, emulsion stability, encapsulation efficiency, moisture content, scanning electron microscopy and oxidation stability were included.The results showed that: before spray dying, Sample 3 ( wall ∶ core is 3 ∶ 5) and Sample 6 ( wall∶ core is 2∶ 3) had high stability, average distributed as well as smaller particle size. On the basis of single factor, we established a mathematical modelusing Design-Expert software.Sample had the best properties with 25% total solids and 15%oil concentration, the encapsulation efficiency reached 97.15% when the outlet air temperature was 160°C.The particles had a round shape with smooth surface and less cracks.This illustrated that wall material Arabic gum and core material soybean germ oil had best ratio and the process conditions of spray dying were also determined.Thiscondition could prevent oil oxidation and extend guarantee period.