Abstract: A lot of natural chlorophyll derivatives, which have special physiological activities, exist naturally in several edible macroalga.In this study, the chlorophylls and their derivatives extracted from six common edible macroalga were reviewed about varieties, chemical structure, transformation and biological activities, these algae included Gracilaria, Porphyra, Laminaria, Undaria, Enteromorpha, and Ulva. The chlorophyll derivatives could be potentially applied in functional foods, cosmetic and pharmaceutical products because of their biological activities such as anti inflammation, anti oxidation, anti tumor and so on.