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荧光纳米材料作为模拟酶在生化分析中的应用进展

关桦楠 王丹丹 孙冰玉 吴永存 张悦

关桦楠,王丹丹,孙冰玉,等. 荧光纳米材料作为模拟酶在生化分析中的应用进展[J]. 食品工业科技,2022,43(12):389−397. doi:  10.13386/j.issn1002-0306.2021030338
引用本文: 关桦楠,王丹丹,孙冰玉,等. 荧光纳米材料作为模拟酶在生化分析中的应用进展[J]. 食品工业科技,2022,43(12):389−397. doi:  10.13386/j.issn1002-0306.2021030338
GUAN Huanan, WANG Dandan, SUN Bingyu, et al. Application Progress of Fluorescent Nanomaterials as Mimic Enzymes in Biochemical Analysis[J]. Science and Technology of Food Industry, 2022, 43(12): 389−397. (in Chinese with English abstract). doi:  10.13386/j.issn1002-0306.2021030338
Citation: GUAN Huanan, WANG Dandan, SUN Bingyu, et al. Application Progress of Fluorescent Nanomaterials as Mimic Enzymes in Biochemical Analysis[J]. Science and Technology of Food Industry, 2022, 43(12): 389−397. (in Chinese with English abstract). doi:  10.13386/j.issn1002-0306.2021030338

荧光纳米材料作为模拟酶在生化分析中的应用进展

doi: 10.13386/j.issn1002-0306.2021030338
基金项目: 黑龙江省科技重大专项项目(2019ZX08B02);国家自然科学基金(31871747,31201376,31370649);黑龙江省自然科学基金(C2016034);哈尔滨商业大学“青年创新人才”支持计划(2019CX05);黑龙江省博士后科研启动项目(LBH-Q19027);黑龙江省领军人才支持计划(2020376)
详细信息
    作者简介:

    关桦楠(1983−),男,博士,教授,研究方向:食品安全检测分析,E-mail:guanhuanan3@163.com

  • 中图分类号: Q599

Application Progress of Fluorescent Nanomaterials as Mimic Enzymes in Biochemical Analysis

  • 摘要: 荧光纳米材料主要包括荧光碳纳米材料、荧光金属纳米材料、多功能复合纳米材料和金属框架等,该材料不仅具有特定的荧光强度和较高的光稳定性,还具有纳米材料特有的量子效应、尺寸小等性质。近年来由于其高稳定性、低成本、易制备等特点逐渐成为模拟酶的优选材料,为食品、医疗和生化领域都带来了崭新的发展机遇。本文简要总结了近年来荧光纳米材料作为模拟酶在生化分析中的应用以及最新的研究进展,并对荧光纳米材料作为模拟酶的未来挑战和前景进行展望。
  • 图  1  基于过氧化物酶样活性和牛血清白蛋白纳米粒荧光开启的双读出碱性磷酸酶检测示意图[36]

    Figure  1.  Schematic illustration for dual-readout ALP detection based on the peroxidase-like activity and fluorescence turn on of BSA-AuNCs[36]

    图  2  H2O2、葡萄糖和尿酸的比色和荧光比率检测示意图[47]

    Figure  2.  Schematic illustration of colorimetric and ratiometric fluorescent detection of H2O2, glucose, and UA[47]

    图  3  双碳点制备及邻苯二胺(OPD)和过氧化氢(H2O2)测定过程示意图[39]

    Figure  3.  Schematic illustration of the preparation of double carbon dots and determination process of o-phenylenediamine (OPD) and hydrogen peroxide (H2O2[39]

    图  4  碳点合成的示意图及双碳点体系中H2Q测定的机理[53]

    Figure  4.  Schematic representation of carbon dots synthesis and the determination mechanism of H2Q in a double carbon dots system[53]

    图  5  用于检测乙酰胆碱和胆碱的荧光方法示意图[59]

    Figure  5.  Schematic representation of the proposed fluorescence method for the detection of acetylcholine and choline[59]

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  • 收稿日期:  2021-03-30
  • 网络出版日期:  2022-04-26
  • 刊出日期:  2022-06-08

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