食源肽螯合钙的研究进展

石景; 邹烨; 马晶晶; 杨彪; 徐为民; 王道营; 杨静

doi:10.13386/j.issn1002-0306.2022070380

食源肽螯合钙的研究进展

doi: 10.13386/j.issn1002-0306.2022070380

石景^{1, 2, 3,},
邹烨^{1, 2, 4},
马晶晶^{1, 2, 4},
杨彪^{1, 2, 4},
徐为民^{1, 2, 4},
王道营^{1, 2, 4, ,},
杨静^{1, 2, 4, ,}

1.
江苏省农业科学院农产品加工研究所，江苏南京 210014
2.
省部共建国家重点实验室培养基地/江苏省食品质量安全重点实验室，江苏南京 210014
3.
南京农业大学食品科技学院，江苏南京 210095
4.
农业农村部农产品冷链物流技术重点实验室，江苏南京 210014

基金项目: 江苏省自然科学基金青年科学基金项目（BK20210160）；国家现代农业产业技术体系资助（CARS-41）。

详细信息

作者简介:
石景（1997−），女，硕士研究生，研究方向：禽肉品加工与质量研究，E-mail：yuyuss29@163.com

通讯作者:
王道营（1979−），男，博士，研究员，研究方向：肉品加工与质量控制，E-mail：wdy0373@aliyun.com

杨静（1986−），女，博士，助理研究员，研究方向：肉品及其副产物加工，E-mail：20210007@jaas.ac.cn

中图分类号: TS251
计量
- 文章访问数: 125
- HTML全文浏览量: 27
- PDF下载量: 11
- 被引次数: 0
出版历程
- 收稿日期: 2022-08-02
- 网络出版日期: 2023-04-18
- 刊出日期: 2023-06-01

Research Progress in Food-derived Calcium Chelated Peptides

SHI Jing^{1, 2, 3
,},
ZOU Ye^{1, 2, 4},
MA Jingjing^{1, 2, 4},
YANG Biao^{1, 2, 4},
XU Weimin^{1, 2, 4},
WANG Daoying^{1, 2, 4
, ,},
YANG Jing^{1, 2, 4
, ,}

1.
Institute of Agricultural Products Processing, Jiangsu Academy of Agricultural Science, Nanjing 210014, China
2.
Jiangsu Provincial Key Laboratory of Food Quality and Safety, A National Key Laboratory Training Base Jointly Established by the Ministry and the Province, Nanjing 210014, China
3.
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
4.
Key Laboratory of Agricultural Products Cold Chain Logistics Technology, Ministry of Agriculture and Rural Affairs, Nanjing 210014, China

摘要

摘要: 钙是人体必需的营养物质，在生命健康中起着重要作用。钙摄入不足常会引发骨质疏松、佝偻病等诸多疾病。近年来随着越来越多的肽螯合钙从食物中制备出来，肽螯合钙稳定性好、生物利用度高等优点备受关注，它也在诸多研究中被视为一类理想的钙源补充剂。本文就食源性肽螯合钙的研究进展进行概述，介绍了肽螯合钙的制备及分离纯化方法，分析了影响其螯合能力的因素，并探讨了其促进钙生物利用度的方式，为肽螯合钙今后在功能性食品上的开发利用提供帮助。
- 肽螯合钙 /
- 分离纯化 /
- 螯合能力 /
- 稳定性 /
- 生物利用度
Abstract: Calcium is an essential nutrient and plays an important role in life and health. Insufficient calcium intake in the body can lead to kinds of diseases, such as rickets and osteoporosis. As more and more calcium chelated peptides are prepared from food in recent years, the advantages of calcium chelated peptides like good stability and high bioavailability have attracted much attention and calcium chelated peptides have been reported to be a kind of ideal calcium supplements. In this paper, the research progress of calcium chelted peptide is summarized, the preparation, separation and purification methods of calcium chelted peptide are introduced, the factors affecting its chelating ability are analyzed, and the ways to promote the bioavailability of calcium are also discussed, in order to provide help for the development and utilization of calcium chelted peptide in functional foods in the future.
- calcium chelated peptide /
- isolation and purification /
- chelated ability /
- stability /
- bioavailability

HTML全文

表 1 肽螯合钙的制备及分离纯化技术

Table 1. Preparation, isolation and purification of calcium chelated peptides

蛋白质来源	制备方法	分离纯化方法	螯合能力	参考文献
鹅骨	酶解法	凝胶过滤色谱法、反相高效液相色谱法	70.08±2.20 mg/g 68.18±1.31 mg/g	周名洋等^[7]
猪	酶解法	−	−	Wu等^[9]
鳗鱼	酶解法	−	56.78 mg/g	吴长平等^[10]
牛、大豆	发酵法	−	707.47±32.16 mg/L	孙晓富等^[14]
黄瓜	发酵法	超滤	−	Wang等^[15]
羊	酶解法、发酵法	−		Wang等^[17]
海参	化学合成法	−	−	Cui等^[32]
小麦	酶解法	超滤、阴离子交换色谱法、凝胶过滤色谱法、反相高效液相色谱法	−	Wang等^[21]
南极磷虾	酶解法	羟基磷灰石色谱法、尺寸排除色谱法、反相高效液相色谱法	0.134 mmol/g	Hou等^[24]
太平洋鳕鱼	酶解法	羟基磷灰色谱法、反相高效液相色谱法	2.53±0.12 μg/mg	Zhang等^[5]
蛋黄	酶解法	阴离子交换色谱法、凝胶过滤色谱法、反相高效液相色谱法	151.10±3.57 mg/g	Zhang等^[26]
米	酶解法	体积排阻色谱法、反相高效液相色谱法	136.2±0.75 mg/g	李超楠^[29]

下载: 导出CSV

表 2 以蛋白质为来源的肽螯合钙的分子量

Table 2. The mass weight of calcium chelated peptides from different protein sources

蛋白质来源	氨基酸序列	钙螯合活力	分子量（Da）	文献
鸡蛋	DEEENDQVK	151.10±3.57 mg/g	1106.44402	Zhang等^[26]
南极磷虾	VLGYIQIR	−	960.58	Hou等^[24]
扁舵鲣	EPAH	76.8±4.5 mg/g	453.3	Chen等^[25]
乙炔对虾	YEIPAEDL	−	948.4	Tam等^[35]
小麦胚芽	FVDVT	89.94%±0.75%	−	Wang等^[21]
罗非鱼	GPAGPHGPVG FDHIVY YQEPVIAPKL	18.80±0.49 mg/g 35.73±0.74 mg/g 28.4±0.94 mg/g	−	Liao等^[36]
罗非鱼	YGTGL LVFL	76.03 μg/mg 79.50 μg/mg	509.25 490.32	Liu等^[37]
酪蛋白	VLPVPQK	129.46 mg/g	779.4960	Liao等^[38]
裂殖壶菌	SSV	136.68±4.6 μg/mg	291.15	Zhang等^[39]
裂殖壶菌	FY	128.77±2.57 μg/mg	−	Cai等^[40]
海参	NDEELNK	−	−	Cui等^[41]

下载: 导出CSV

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