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中国精品科技期刊2020
王佩欣,卢菲艳,张露,等. 不同产地覆盆子乙醇提取物中的酚类物质及其抗糖尿病活性[J]. 食品工业科技,2024,45(9):1−8. doi: 10.13386/j.issn1002-0306.2023060301.
引用本文: 王佩欣,卢菲艳,张露,等. 不同产地覆盆子乙醇提取物中的酚类物质及其抗糖尿病活性[J]. 食品工业科技,2024,45(9):1−8. doi: 10.13386/j.issn1002-0306.2023060301.
WANG Peixin, LU Feiyan, ZHANG Lu, et al. Phenolic Compounds and Antidiabetic Activity of Raspberry Ethanol Extract from Different Producing Areas[J]. Science and Technology of Food Industry, 2024, 45(9): 1−8. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023060301.
Citation: WANG Peixin, LU Feiyan, ZHANG Lu, et al. Phenolic Compounds and Antidiabetic Activity of Raspberry Ethanol Extract from Different Producing Areas[J]. Science and Technology of Food Industry, 2024, 45(9): 1−8. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023060301.

不同产地覆盆子乙醇提取物中的酚类物质及其抗糖尿病活性

Phenolic Compounds and Antidiabetic Activity of Raspberry Ethanol Extract from Different Producing Areas

  • 摘要: 本文以六个产地(广东、广西、安徽、浙江、江西和四川)的覆盆子为原料,采用乙醇提取法提取覆盆子酚类物质,对比分析酚类物质及其抗糖尿病活性。结果表明,在不同产地中,广东覆盆子总酚含量最高(349.77 μg GAE/mg E),浙江覆盆子总黄酮含量最高(202.55 μg QUE/mg E),四川覆盆子提取物中的水解单宁含量最高(125.07 mg GAE/g E)。从六个产地的覆盆子提取物中鉴定出了34种酚类化合物,主要是鞣花单宁、黄酮和酚酸类物质。活性研究显示,四川覆盆子提取物具有最强的DPPH·清除能力(IC50=63.069 μg/mL)、ABTS+·清除能力(IC50=29.977 μg/mL)和α-葡萄糖苷酶抑制能力(IC50=0.086 mg/mL),安徽覆盆子提取物抑制AGEs形成的能力相对较强(81.91%)。综上,四川产地覆盆子是抗糖尿病药物的优质来源。

     

    Abstract: In this paper, phenolic compounds of raspberry from six producing areas (Guangdong, Guangxi, Anhui, Zhejiang, Jiangxi and Sichuan) were extracted by ethanol extraction method, and the phenolic compounds and their antidiabetic activities were compared and analyzed. The results showed that the content of polyphenol of raspberry from Guangdong was the highest (349.77 μg GAE/mg E), Zhejiang raspberry showed the highest total flavonoid content (202.55 μg QUE/mg E), while Sichuan raspberry showed the highest content of hydrolyzed tannin (125.07 mg GAE/g E). Thirty-four different phenolic compounds were identified from raspberry extracts, which were mainly ellagitannins, flavonoids and phenolic acids. Studies on antidiabetic activity showed that the DPPH· (IC50=63.069 μg/mL) and ABTS+· scavenging capacities (IC50=29.977 μg/mL) and the inhibitory effect on α-glycosidase (IC50=0.086 mg/mL) of raspberry extracts from Sichuan were higher than those from other regions, whereas Anhui raspberry extract showed the strongest inhibitory ability of AGEs (81.91%). In summary, raspberry from Sichuan is a high-quality source of anti-diabetes drugs.

     

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