Study of the effect of fish egg peptides binding with calcium on increasing calcium bioavailability in rats

The promoting effect of fish egg peptides binding with calcium ( EPP- Ca) on increasing calcium bioavailability in rats was studied in this paper. After EPP- Ca supplement for 4 weeks, the rats' body weight increased 25.53%, calcium absorption rate reached 65.28%, serum calcium and the activity of serum alkaline phosphatase came back to 2.58mmol /L and 177.13U /L respectively, femur weight, calcium content and bone mineral density respectively arrived to 877.31mg、0.22g /cm2and 254.75mg /g. Furthermore, EPP- Ca was more efficient than inorganic calcium on increasing calcium bioavailability in rats and had similar effect with casein phospeptides binding with calcium ( CPP- Ca) . Thus, it is possible to provide utilization of EPP- Ca as a novel calcium nutraceutical additive in food industry.