Effects of different extraction technologies on the extraction yield for Ledum Ursolic acid

To study the effects of different extraction technologies on the extraction rates of Ursolic Acid from Lduem. Ursolic Acid was extracted by ultrasonic treatment, extraction in room temperature for 24 h and flash extraction.The extraction rates and the changes of the surface structure of Ursolic Acid after treated by the three above- mentioned extraction methods were investigated, while the relationships between the changes and the extraction rates of Ursolic Acid were analyzed. The results showed that the extraction rates of Ursolic Acid by ultrasonic treatment for 30 minutes, extraction in room temperature for 24 h and flash extraction for 3minutes were in order of 0.58%, 0.83% and 1.18%. From the structure of the surface material, more serious of the crushing of material, extraction rate was higher, and more impurities.The order of the fragmentation degree of the material was flash extraction, ultrasonic treatment and extraction in room temperature. Therefore, from the point of Ursolic Acid extraction rate, flash extraction was superior to ultrasonic treatment and flash extraction for 3 minutes was appropriate.