Effect of Cordyceps taishanensis polysaccharide on protein content in serum and antioxidant activity in immunosuppressive mice

Objective: To study the effects of Cordyceps taishanensis polysaccharide ( CTP) on protein content in serum and antioxidant activity in immunosuppressive mice. Methods: Through gavage experiments in mice, the effects of CTP on the amount of total proteins ( TP) , albumin ( ALB) and globulin ( GLO) in serum and antioxidant activity were analyzed.Results: Compared with the CY model group, the amount of TP, ALB and GLO in serum were increased significantly ( p < 0.01) , the activities of superoxide dismutase ( SOD) in erythrocytes and catalase ( CAT) in serum were significantly increased ( p < 0.05 or p < 0.01) and the content of malondialdehyde ( MDA) in erythrocytes were decreased significantly ( p < 0.01) in the three CTP treatment groups. Conclusion: CTP could significantly increase protein content in serum and reduce the damage at some level to liver function of immunosuppressive mice induced by CY. CTP could also improve antioxidant activity of CY- induced immunosuppressive mice to a certain extent.