Ameliorative Effect of Poria cocos-Yam Riched Rice Paste and Hericium erinaceus Biscuit on Rats with Functional Dyspepsia

Effect of rice paste based on Poria cocos-yam extract and biscuit riched in Hericium erinaceus extract on functional dyspepsia in rats were investigated. Functional dyspepsia rat mblished, and rats were randomly divided into model-, positive-, Poria cocos-yam extracts-(low, medium and high dose), rice paste-(low, medium and high dose), Hericium erainaceus extract-(low, medium and high dose), and biscuit-(low, medium and high dose) treated groups. The corresponding materials were orally administered for 14 days. The results showed that giving the four materials significantly (P<0.05) increased the body weight, feed intake, gastric emptying rate, small intestinal propulsion rate, serum motilin and gastrin levels, and significantly (P<0.05) reduced serum cholecystokinin level in rats with functional dyspepsia, with the colonic levels of acetic-, propionic-, butyric- and total short-chain fatty acids also increased. In summary, the four materials could effectively ameliorate the symptoms of functional dyspepsia in rats, while Poria cocos-yam extract and rice paste functioned better than Hericium erinaceus extract and biscuit, the extracts exerted similar effect with the corresponding products, and the medium dose showed the best effect. The results of this study could provide data to support the development of products which improved gastrointestinal function and health.